Alternative Strategy for Adjusting the Association Specificity of Hydrogen-Bonded Duplexes

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• 作者：Penghui Zhang ; Hongzhu Chu ; Xianghui Li ; Wen Feng ; Pengchi Deng ; Lihua Yuan ; Bing Gong
• 刊名：Organic Letters
• 出版年：2011
• 出版时间：January 7, 2011
• 年：2011
• 卷：13
• 期：1
• 页码：54-57
• 全文大小：285K
• 年卷期：v.13,no.1(January 7, 2011)
• ISSN：1523-7052

文摘

A strategy for creating new association specificity of hydrogen-bonded duplexes by varying the spacings between neighboring hydrogen bonds is described. Incorporation of naphthalene-based residues has provided oligoamide strands that pair into duplexes sharing the same H-bonding sequences (e.g., DDAA) but differing in the spacings between their intermolecular hydrogen bonds, leading to homo- or heteroduplexes. The ability to manipulate association-specificity as demonstrated by this work may be extended to other multiple hydrogen bonded systems, thereby further enhancing the diversity of multiple hydrogen-bonded association units for constructing supramolecular structures.