C-Geranyl Compounds from Paulownia tomentosa Fruits

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• 作者：Karel //pubs.acs.org/images/entities/Scaron.gif" border="0">mejkal ; Lenka Grycová ; Radek Marek ; Filip Lemiè ; re ; Dagmar Jankovská ; Hana Forejtní ; ková ; J&
• 刊名：Journal of Natural Products
• 出版年：2007
• 出版时间：August 2007
• 年：2007
• 卷：70
• 期：8
• 页码：1244 - 1248
• 全文大小：83K
• 年卷期：v.70,no.8(August 2007)
• ISSN：1520-6025

文摘

Five geranylflavonoids, one prenylated flavonoid, and a simple flavanone were isolated from an ethanolic extract ofPaulownia tomentosa fruit. Tomentodiplacol (1), 3'-O-methyl-5'-methoxydiplacol (2), 6-isopentenyl-3'-O-methyltaxifolin(3), and dihydrotricin (4) are reported from a natural source for the first time and 3'-O-methyldiplacone (6) for the firsttime from the genus Paulownia. The structures of the compounds were determined by mass spectrometry, includingHRMS, and by 1D and 2D NMR spectroscopy. The cytotoxicity and DPPH (2,2-diphenyl-1-picrylhydrazyl)-quenchingactivity of some of these compounds were tested, with diplacone proving to be the best antioxidant, although the mostcytotoxic compound.