Comparative Study of Ovatifolin Antioxidant and Growth Inhibition Activities
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文摘
A comparative study on the effect of arturin (1), ovatifolin (3), deacetylovatifolin (5), and their1-acetoxyarturin (2), 8-acetoxyovatifolin (4), 1,10-epoxyovatifolin (6), and 11,13-dihydroovatifolin(7) derivatives, isolated from Podanthus ovatifolius and Podanthus mitiqui, on the seedling growth,germination, and respiration of several monocot and dicot weedy target species was carried out. Inaddition to the inhibitory activity on the bleaching of crocin induced by alkoxyl radicals, thesecompounds also displayed scavenging properties toward DPPH in TLC autographic and spectrophotometric assays. The results indicate that ovatifolin (3), deacetylovatifolin (5), epoxyovatifolin(6), dihydroovatifolin (7), and the CH2Cl2 extract interfere with pre-emergence of seedlings at thelevel of respiration. These compounds appear to have selective effects on the radicle and shoot growthof Physalis ixocarpa and Trifolium pratense. Their allelopathic effects are comparable to those ofparthenolide, a know natural growth inhibitor.Keywords: Podanthus ovatifolius; P. mitiqui; ovatifolin; germacrane; sesquiterpene lactone;Asteraceae; phytogrowth inhibition; seed respiration; radical scavengers; DPPH

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