Sarglaperoxides A and B, Sesquiterpene–Normonoterpene Conjugates with a Peroxide Bridge from the Seeds of Sarcandra glabra
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- 作者：Peng Wang ; Rui-Jun Li ; Rui-Huan Liu ; Kai-Li Jian ; Ming-Hua Yang ; Lei Yang ; Ling-Yi Kong ; Jun Luo
- 刊名：Organic Letters
- 出版年：2016
- 出版时间：February 19, 2016
- 年：2016
- 卷：18
- 期：4
- 页码：832-835
- 全文大小：284K
- ISSN：1523-7052
文摘
Sarglaperoxides A (1) and B (2), a pair of unusual sesquiterpene–normonoterpene conjugates with a peroxide bridge, were isolated from the seeds of Sarcandra glabra. The structures and absolute configurations of 1 and 2 were determined on the basis of spectroscopic data analysis, including MS, NMR, CD, and XRD. The two compounds were screened in antimicrobial, anti-inflammatory, and cytotoxic bioassays and showed moderate bioactivities.