Turn-on Phosphorescent Chemodosimeter for Hg2+ Based on a Cyclometalated Ir(III) Complex and Its Application in Time-Resolved Luminescence Assays and Live Cell Imaging

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• 作者：Jia-Xi Ru ; Li-Ping Guan ; Xiao-Liang Tang ; Wei Dou ; Xiang Yao ; Wan-Min Chen ; Ya-Ming Liu ; Guo-Lin Zhang ; Wei-Sheng Liu ; Yue Meng ; Chun-Ming Wang
• 刊名：Inorganic Chemistry
• 出版年：2014
• 出版时间：November 3, 2014
• 年：2014
• 卷：53
• 期：21
• 页码：11498-11506
• 全文大小：601K
• ISSN：1520-510X

文摘

A novel 鈥渢urn-on鈥?phosphorescent chemodosimeter based on a cyclometalated Ir(III) complex has been designed and synthesized, which displays high selectivity and sensitivity toward Hg²⁺ in aqueous media with a broad pH range of 4鈥?0. Furthermore, by time-resolved photoluminescence techniques, some interferences from the short-lived background fluorescence can be eliminated effectively and the signal-to-noise ratio of the emission detection can be improved distinctly by using the chemodosimeter. Finally, the chemodosimeter can be used to monitor Hg²⁺ effectively in living cells by confocal luminescence imaging.