Rhodium(III)-Catalyzed Intermolecular Amidation with Azides via C(sp3)鈥揌 Functionalization
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- 作者：Nuancheng Wang ; Renhe Li ; Liubo Li ; Shansheng Xu ; Haibin Song ; Baiquan Wang
- 刊名：Journal of Organic Chemistry
- 出版年：2014
- 出版时间：June 6, 2014
- 年：2014
- 卷：79
- 期：11
- 页码：5379-5385
- 全文大小：405K
- 年卷期：v.79,no.11(June 6, 2014)
- ISSN：1520-6904
文摘
The amidation reactions of 8-methylquinolines with azides catalyzed by a cationic rhodium(III) complex proceed efficiently to give quinolin-8-ylmethanamine derivatives in good yields via C(sp3)鈥揌 bond activation under external oxidant-free conditions. A catalytically competent five-membered rhodacycle has been isolated and characterized, revealing a key intermediate in the catalytic cycle.