General and Selective Iron-Catalyzed Transfer Hydrogenation of Nitroarenes without Base

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• 作者：Gerrit Wienh枚fer ; Iv谩n Sorribes ; Albert Boddien ; Felix Westerhaus ; Kathrin Junge ; Henrik Junge ; Rosa Llusar ; Matthias Beller
• 刊名：Journal of the American Chemical Society
• 出版年：2011
• 出版时间：August 17, 2011
• 年：2011
• 卷：133
• 期：32
• 页码：12875-12879
• 全文大小：795K
• 年卷期：v.133,no.32(August 17, 2011)
• ISSN：1520-5126

文摘

The first well-defined iron-based catalyst system for the reduction of nitroarenes to anilines has been developed applying formic acid as reducing agent. A broad range of substrates including other reducible functional groups were converted to the corresponding anilines in good to excellent yields at mild conditions. Notably, the process constitutes a rare example of base-free transfer hydrogenations.