An Improved Method for the Synthesis of F-BODIPYs from Dipyrrins and Bis(dipyrrin)s

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• 作者：Travis Lundrigan ; Alexander E. G. Baker ; Lauren E. Longobardi ; Tabitha E. Wood ; Deborah A. Smithen ; Sarah M. Crawford ; T. Stanley Cameron ; Alison Thompson
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：April 20, 2012
• 年：2012
• 卷：14
• 期：8
• 页码：2158-2161
• 全文大小：241K
• 年卷期：v.14,no.8(April 20, 2012)
• ISSN：1523-7052

文摘

An improved methodology for the synthesis of F-BODIPYs from dipyrrins and bis(dipyrrin)s is reported. This strategy employs lithium salts of dipyrrins as intermediates that are then treated with only 1 equiv of boron trifluoride diethyletherate to obtain the corresponding F-BODIPYs. This scalable route to F-BODIPYs renders high yields with a facile purification process involving merely filtration of the reaction mixture through Celite in many cases.