[Pd(渭-Br)(PtBu3)]2 as a Highly Active Isomerization Catalyst: Synthesis of Enol Esters from Allylic Esters

详细信息    查看全文

• 作者：Patrizia Mamone ; Matthias F. Gr眉nberg ; Andreas Fromm ; Bilal A. Khan ; Lukas J. Goo脽en
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：July 20, 2012
• 年：2012
• 卷：14
• 期：14
• 页码：3716-3719
• 全文大小：256K
• 年卷期：v.14,no.14(July 20, 2012)
• ISSN：1523-7052

文摘

The dimeric Pd(I)-complex [Pd(渭-Br)(P^tBu₃)]₂ was found to be highly active for catalyzing double-bond migration in various substrates such as unsaturated ethers, alcohols, amides, and arenes, under mild conditions. It efficiently mediates the conversion of allylic esters into enol esters, rather than inserting into the allylic C鈥揙 bond. The broad applicability of this reaction was demonstrated with the synthesis of 22 functionalized enol esters.