Palladium Complexes of Planar Chiral Ferrocenyl Phosphine-NHC Ligands: New Catalysts for the Asymmetric Suzuki−Miyaura Reaction

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• 作者：Nathalie Debono ; Agns Labande ; Eric Manoury ; Jean-Claude Daran ; Rinaldo Poli
• 刊名：Organometallics
• 出版年：2010
• 出版时间：April 26, 2010
• 年：2010
• 卷：29
• 期：8
• 页码：1879-1882
• 全文大小：797K
• 年卷期：v.29,no.8(April 26, 2010)
• ISSN：1520-6041

文摘

Air-stable neutral and cationic palladium complexes bearing chiral phosphine-N-heterocyclic carbene ligands with planar chirality only have been prepared in moderate to good yields and characterized by NMR and X-ray diffraction studies. They are shown to catalyze the asymmetric coupling of aryl bromides with arylboronic acids in good yields and moderate enantioselectivities (up to 42% ee) with low catalyst loadings (0.1−0.5 mol %).