Inkjet-Printed Bioassays for Direct Reading with a Multimode DVD/Blu-Ray Optical Drive

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• 作者：Xiaochun Li ; Maolin Shi ; Caie Cui ; Hua-Zhong Yu
• 刊名：Analytical Chemistry
• 出版年：2014
• 出版时间：September 16, 2014
• 年：2014
• 卷：86
• 期：18
• 页码：8922-8926
• 全文大小：318K
• ISSN：1520-6882

文摘

Compact disc-based bioassays have been developed as novel point-of-care (POC) tools for various applications in chemical analysis and biomedical diagnosis. For the fabrication of assay discs, the surface patterning and sample introduction have been restricted to manual delivery that is unfavorable for on-demand high throughput medical screening. Herein, we have adapted a conventional inkjet printer to prepare bioassays on regular DVD-Rs and accomplished quantitative analysis with a multimode DVD/Blu-Ray optical drive in conjunction with free disc diagnostic software. The feasibility and accuracy of this method have been demonstrated by the quantitative analysis of inkjet-printed biotin鈥搒treptavidin binding assays on DVD, which serves as a trial system for other complex, medically relevant sandwich-format or competitive immunoassays.