First Total Synthesis of a Polyunsaturated Chromone Metabolite Isolated from the Brown Algae Zonaria tournefortii

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• 作者：Hany F. Anwar ; Trond Vidar Hansen
• 刊名：Organic Letters
• 出版年：2009
• 出版时间：February 5, 2009
• 年：2009
• 卷：11
• 期：3
• 页码：587-588
• 全文大小：91K
• 年卷期：v.11,no.3(February 5, 2009)
• ISSN：1523-7052

文摘

Starting from the ethyl ester of eicosapentaenoic acid, the first total synthesis of the marine natural product all-(Z)-5,7-dihydroxy-2-(4Z,7Z,10Z,13Z,16Z-nonadecapentaenyl)chromone has been achieved in six steps and in 14% overall yield.