Thermoactuated Diffusion Control in Soft Matter Nanofluidic Devices

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• 作者：Martin Markstr&ouml ; m ; Ludvig Lizana ; Owe Orwar ; Aldo Jesorka
• 刊名：Langmuir
• 出版年：2008
• 出版时间：May 6, 2008
• 年：2008
• 卷：24
• 期：9
• 页码：5166 - 5171
• 全文大小：203K
• 年卷期：v.24,no.9(May 6, 2008)
• ISSN：1520-5827

文摘

The diffusive transport rate in a soft matter nanofluidic device is controlled with a thermoactuated hydrogel valve.The device consists of three giant unilamellar vesicles linearly conjugated by lipid nanotubes, with a solution of thestimuli-responsive polymer poly(N-isopropyl acrylamide) (PNIPAAm) in the central vesicle. The valve states "high(transport) rate" and "low (transport) rate" are obtained by heat-activated switching between PNIPAAm's dissolvedand compact aggregated states. We show that three parameters influence the diffusion rate within the device: theincrease of the transport rate caused by a decrease in PNIPAAm concentration upon compaction, the temperaturedependence of the buffer viscosity, and the volume excluded by the PNIPAAm hydrogel compartment.