Palladium-Catalyzed Intramolecular Insertion of Alkenes into the Carbon鈥揘itrogen Bond of 尾-Lactams

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• 作者：Akira Yada ; Satoshi Okajima ; Masahiro Murakami
• 刊名：Journal of the American Chemical Society
• 出版年：2015
• 出版时间：July 15, 2015
• 年：2015
• 卷：137
• 期：27
• 页码：8708-8711
• 全文大小：354K
• ISSN：1520-5126

文摘

The carbon鈥搉itrogen bond of 尾-lactams is cleaved by palladium(0), and an alkene is intramolecularly inserted therein. The following reductive elimination produces nitrogen-containing benzo-fused tricycles in good to high yields.