Ruthenium-Catalyzed Hydroformylation/Reduction of Olefins to Alcohols: Extending the Scope to Internal Alkenes

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• 作者：Lipeng Wu ; Ivana Fleischer ; Ralf Jackstell ; Irina Profir ; Robert Franke ; Matthias Beller
• 刊名：Journal of the American Chemical Society
• 出版年：2013
• 出版时间：September 25, 2013
• 年：2013
• 卷：135
• 期：38
• 页码：14306-14312
• 全文大小：426K
• 年卷期：v.135,no.38(September 25, 2013)
• ISSN：1520-5126

文摘

In the presence of 2-phosphino-substituted imidazole ligands and Ru₃(CO)₁₂ or Ru(methylallyl)₂(COD) direct hydroformylation and hydrogenation of alkenes to alcohols takes place. In addition to terminal alkenes, also more challenging internal olefins are converted preferentially to industrially important linear alcohols in high yield (up to 88%) and regioselectivity (n:iso up to 99:1).