Enantioselective, Catalytic Trichloromethylation through Visible-Light-Activated Photoredox Catalysis with a Chiral Iridium Complex

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• 作者：Haohua Huo ; Chuanyong Wang ; Klaus Harms ; Eric Meggers
• 刊名：Journal of the American Chemical Society
• 出版年：2015
• 出版时间：August 5, 2015
• 年：2015
• 卷：137
• 期：30
• 页码：9551-9554
• 全文大小：398K
• ISSN：1520-5126

文摘

An enantioselective, catalytic trichloromethylation of 2-acyl imidazoles and 2-acylpyridines is reported. Several products are formed with enantiomeric excess of 鈮?9%. In this system, a chiral iridium complex serves a dual function, as a catalytically active chiral Lewis acid and simultaneously as a precursor for an in situ assembled visible-light-triggered photoredox catalyst.