Vertically Aligned Carbon Nanofiber Arrays Record Electrophysiological Signals from Hippocampal Slices

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• 作者：Zhe Yu ; Timothy E. McKnight ; M. Nance Ericson ; Anatoli V. Melechko ; Michael L. Simpson ; Barclay Morrison III
• 刊名：Nano Letters
• 出版年：2007
• 出版时间：August 2007
• 年：2007
• 卷：7
• 期：8
• 页码：2188 - 2195
• 全文大小：641K
• 年卷期：v.7,no.8(August 2007)
• ISSN：1530-6992

文摘

Vertically aligned carbon nanofiber (VACNF) electrode arrays were tested for their potential application in recording neuro-electrophysiologicalactivity. We report, for the first time, stimulation and extracellular recording of spontaneous and evoked neuroelectrical activity in organotypichippocampal slice cultures with ultramicroelectrode VACNF arrays. Because the electrodes are carbon-based, these arrays have potentialadvantages over metal electrodes and could enable a variety of future applications as precise, informative, and biocompatible neural interfaces.