Saponins and Polyphenols from Fadogia ancylantha (Makoni Tea)

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• 作者：Teresa Mencherini ; Patrizia Picerno ; Pasquale Del Gaudio ; Michela Festa ; Anna Capasso ; Rita Aquino
• 刊名：Journal of Natural Products
• 出版年：2010
• 出版时间：February 26, 2010
• 年：2010
• 卷：73
• 期：2
• 页码：247-251
• 全文大小：112K
• 年卷期：v.73,no.2(February 26, 2010)
• ISSN：1520-6025

文摘

Three new saponins (1−3) and a known saponin, together with four known polyphenolic compounds, have been isolated from the fermented and dried leaves of Fadogia ancylantha (Makoni tea). The structures of compounds 1−3 were established by analysis of their spectroscopic data. Both an ethanol−water extract of F. ancylantha and its phenolic constituents showed significant free-radical-scavenging and antimicrobial activities. No cytotoxicity, as evaluated by analysis of hypodiploid nuclei in HUVEC cells using propidium iodide staining, was observed for either the plant crude extract or its constituents.