An Enantioselective Approach to 4-O-Protected-2-cyclopentene-l,4-diol Derivatives via a Rhodium-Catalyzed Redox-Isomerization Reaction

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• 作者：Kai Ren ; Mengmeng Zhao ; Bei Hu ; Bin Lu ; Xiaomin Xie ; Virginie Ratovelomanana-Vidal ; Zhaoguo Zhang
• 刊名：Journal of Organic Chemistry
• 出版年：2015
• 出版时间：December 18, 2015
• 年：2015
• 卷：80
• 期：24
• 页码：12572-12579
• 全文大小：490K
• ISSN：1520-6904

文摘

Kinetic resolution of a series of cyclopentene-1,4-diol derivatives has been successfully achieved with enantiomeric excess up to 99.4% and a k_f/k_s ratio of 55 by a rhodium-catalyzed redox-isomerization reaction in a noncoordinating solvent.