Fiber Introduction Mass Spectrometry: Fully Direct Coupling of Solid-Phase Microextraction with Mass Spectrometry
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- 作者：Eduardo C. Meurer ; Daniela M. Tomazela ; Rogerio C. Silva ; Fabio Augusto ; and Marcos N. Eberlin
- 刊名：Analytical Chemistry
- 出版年：2002
- 出版时间：November 1, 2002
- 年：2002
- 卷：74
- 期：21
- 页码：5688 - 5692
- 全文大小：129K
- 年卷期：v.74,no.21(November 1, 2002)
- ISSN：1520-6882
文摘
This work describes the first fully direct coupling of solid-phase microextraction (SPME) with mass spectrometry.An inlet system using a septum as the only interfacebetween the ambient and the high-vacuum mass spectrometer was constructed to allow the introduction of theSPME needle directly into the ionization region of a massspectrometer. The PDMS-coated fiber was then placedand exposed exactly between the two ionization filaments.Uniform heating of the fiber, efficient thermal desorption,and electron ionization of the analytes were achieved.Using this new analytical technique, here termed fiberintroduction mass spectrometry (FIMS), we have beenable to detect and quantitate several volatile (VOC) andsemivolatile (SVOC) organic chemicals (carbon tetrachloride, benzene, toluene, xylenes, 
chars/gamma.gif" BORDER=0 >-terpinene, diisoamylether, chlorobenzene, and many PAHs) and two herbicides (Sylvex and its methyl ether) from aqueous solutionsat low-ppb to ppt levels using either SPME headspace orsolution extraction. FIMS shows high sensitivity (ng/L),good reproducibility, and accuracy, providing thereforea simple and effective approach to rapid analysis of VOCand SVOC in various matrixes.
chars/gamma.gif" BORDER=0 >-terpinene, diisoamylether, chlorobenzene, and many PAHs) and two herbicides (Sylvex and its methyl ether) from aqueous solutionsat low-ppb to ppt levels using either SPME headspace orsolution extraction. FIMS shows high sensitivity (ng/L),good reproducibility, and accuracy, providing thereforea simple and effective approach to rapid analysis of VOCand SVOC in various matrixes.