A Novel Route to 2-Cyclohexenones via Reaction of the Manganese Carbene Anions [(5-MeC5H4)(CO)2<
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- 作者：Carole Mongin ; Noë ; l Lugan ; and René ; Mathieu
- 刊名：Organometallics
- 出版年：1997
- 出版时间：September 2, 1997
- 年：1997
- 卷：16
- 期：18
- 页码：3873 - 3875
- 全文大小：156K
- 年卷期：v.16,no.18(September 2, 1997)
- ISSN：1520-6041
文摘
The carbene anions[Cp'(CO)2Mn=C(OEt)CHR]- ([1]-, Cp' =
5-MeC5H4; R = H, Me) react at-78
C with the 
,
-unsaturated ketonesR1(H)C=C(H)C{O}Me (2, R1 = H, Me, Ph) to give the MichaeladductsCp'(CO)2Mn=C(OEt)CH(R)CH(R1)CH2C{O}Me(3) uponacidic hydrolysis at low temperature. By contrast,quenching the reaction after warming up to room temperature allows isolation of the cyclohexenone complexesCp'(CO)2Mn(2-CH=CHCH(R)CH(R1)CH2 C{O})(5), fromwhich the corresponding substituted 2-cyclohexenones(9)can be readily released by reaction with triphenylphosphine or carbon monoxide.
5-MeC5H4; R = H, Me) react at-78C with the ,-unsaturated ketonesR1(H)C=C(H)C{O}Me (2, R1 = H, Me, Ph) to give the MichaeladductsCp'(CO)2Mn=C(OEt)CH(R)CH(R1)CH2C{O}Me(3) uponacidic hydrolysis at low temperature. By contrast,quenching the reaction after warming up to room temperature allows isolation of the cyclohexenone complexes2-