Absolute Conformation and Substituent Effects on Chiroptical Properties of 9-(2-Halo-1,1-dimethylethyl)-11,12- bis(methoxycarbonyl)-9,10-dihydro-9,10-ethenoanthracenes

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• 作者：Shinji Toyota ; Tadashi Akinaga ; Hiroharu Kojima ; Michihiko Aki ; and Michinori <img src="http ; //pubs.acs.org/images/entities/Omacr.gif" border="0">ki
• 刊名：Journal of the American Chemical Society
• 出版年：1996
• 出版时间：November 20, 1996
• 年：1996
• 卷：118
• 期：46
• 页码：11460 - 11466
• 全文大小：333K
• 年卷期：v.118,no.46(November 20, 1996)
• ISSN：1520-5126

文摘

Optically active and inactive rotational isomers of9-(1,1-dimethyl-3-butenyl)-11,12-bis(methoxycarbonyl)-9,10-dihydro-9,10-ethenoanthracene were isolated. Theabsolute conformations of these optically activeconformerswere determined by correlating them with those of camphorsultam amidesof 9-(2-carboxy-1,1-dimethylethyl)-11,12-bis(methoxycarbonyl)-9,10-dihydro-9,10-ethenoanthracenes,the latter being determined by X-ray analysis. Fromthe carboxylic acids, the title compounds, in which the halogen is achloro, a bromo, or an iodo, were prepared. TheCD spectra of the title compounds showed remote substituent effects onthe Cotton effect at ca. 220 nm.