Retention of Configuration on the Oxidative Addition of P-H Bond to Platinum (0) Complexes: The First Straightforward Synthesis of Enantiomerically Pure P-Chiral Alkenylphosphinates via Palladium-Cata
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- 作者：Li-Biao Han ; Chang-Qiu Zhao ; Shun-ya Onozawa ; Midori Goto ; and Masato Tanaka
- 刊名：Journal of the American Chemical Society
- 出版年：2002
- 出版时间：April 17, 2002
- 年：2002
- 卷：124
- 期：15
- 页码：3842 - 3843
- 全文大小：48K
- 年卷期：v.124,no.15(April 17, 2002)
- ISSN：1520-5126
文摘
The oxidative addition of pure (RP)-menthyl phenylphosphinate 1 to a platinum (0) complex proceeds readily with retention of configuration at the chiral phosphorus center which was unambiguously confirmed by an X-ray analysis. In the presence of a catalytic amount of palladium, the hydrophosphinylation of a variety of alkynes with 1 also takes place stereospecifically, with retention of configuration, affording high yields of the corresponding vinylphosphinates bearing a single chirality at phosphorus.