7,7-Dimethylaporphine and Other Alkaloids from the Bark of Guatteria friesiana
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- 作者：Emmanoel V. Costa ; Maria Lúcia B. Pinheiro ; Beatriz Helena L. N. S. Maia ; Francisco A. Marques ; Ana Lúcia T. G. Ruiz ; Gabriela M. Marchetti ; João Ernesto de Carvalho ; Milena B. P. Soares ; Cinara O. S. Costa ; Alexandre F. C. Galvão ; Norberto P. Lopes ; Hector H. F. Koolen ; Daniel P. Bezerra ; Andersson Barison
- 刊名：Journal of Natural Products
- 出版年：2016
- 出版时间：June 24, 2016
- 年：2016
- 卷：79
- 期：6
- 页码：1524-1531
- 全文大小：312K
- 年卷期：0
- ISSN：1520-6025
文摘
Phytochemical investigation of the bark of Guatteria friesiana afforded 12 new aporphines (<b>1b>–<b>12b>), along with nine known alkaloids (<b>13b>–<b>21b>). The structures of the new alkaloids were determined on the basis of spectroscopic data interpretation. The cytotoxic activity of the isolated compounds against a small panel of tumor cell lines was assessed using the Alamar blue assay.