Synthesis of Indolyl Imidazole Derivatives via Base-Promoted Tandem Reaction of N-[2-(1-Alkynyl)phenyl]carbodiimides with Isocyanides

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• 作者：Wenyan Hao ; Yuanyuan Jiang ; Mingzhong Cai
• 刊名：Journal of Organic Chemistry
• 出版年：2014
• 出版时间：April 18, 2014
• 年：2014
• 卷：79
• 期：8
• 页码：3634-3640
• 全文大小：273K
• 年卷期：v.79,no.8(April 18, 2014)
• ISSN：1520-6904

文摘

An efficient route to indolyl imidazole derivatives has been developed through a base-promoted tandem reaction of N-[2-(1-alkynyl)phenyl]carbodiimides with isocyanides in DMSO at 40 掳C. The present tandem process allows the assembly of a variety of indolyl imidazole derivatives in moderate to good yields.