Rhabdastrellins A−F, Isomalabaricane Triterpenes from the Marine Sponge Rhabdastrella aff. distincta
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- 作者：Fang Lv ; Minjuan Xu ; Zhiwei Deng ; Nicole J. de Voogd ; Rob W. M. van Soest ; Peter Proksch ; Wenhan Lin
- 刊名：Journal of Natural Products
- 出版年：2008
- 出版时间：October 24, 2008
- 年：2008
- 卷：71
- 期：10
- 页码：1738-1741
- 全文大小：128K
- 年卷期：v.71,no.10(October 24, 2008)
- ISSN：1520-6025
文摘
Chemical examination of the marine sponge Rhabdastrella aff. distincta resulted in the isolation of six new isomalabaricane triterpenes, rhabdastrellins A−F (1−6), which were present as minor components, along with stellettins L and M. Their structures were elucidated on the basis of extensive spectroscopic data analyses and comparison with spectroscopic data of known analogues. The cytotoxicity of compounds 1−6 against a small panel of human tumor cell lines was also evaluated.