A Comparative Study of Several Techniques to Obtain Fatty Acid Nanoparticles: Palmitic Acid

详细信息    查看全文

• 作者：R. Benages ; L. Bays ; R. Cordobilla ; E. Moreno ; T. Calvet ; Miquel A. Cuevas-Diarte*
• 刊名：Crystal Growth & Design
• 出版年：2009
• 出版时间：April 1, 2009
• 年：2009
• 卷：9
• 期：4
• 页码：1762-1766
• 全文大小：295K
• 年卷期：v.9,no.4(April 1, 2009)
• ISSN：1528-7505

文摘

The aim of this study is to obtain fatty acid nanoparticles, especially of palmitic acid. Some synthetic paths were carried out: reprecipitation method, hot homogenization technique, and microemulsions. A qualitative comparison of particle size obtained with these and traditional methods such as dissolution/evaporation, melting/quenching, and sublimation were performed. The hot homogenization technique with addition of small amounts of aluminum chloride has been found to be suitable to obtain a narrow distribution of nanoparticles. Electron diffraction was attempted to characterize the crystal form obtained from the hot homogenization technique; nevertheless, the obtained phase cannot be identified due to overlapping reflections of the different fatty acid phases.