Kinetic Resolution of Secondary Alcohols by the Combination of a Chiral Br酶nsted Acid, DABCO, and Acetyl Chloride
文摘
An efficient and simple protocol for the kinetic resolution of secondary alcohols is presented. The new system is based on a combination of chiral Br酶nsted acid, DABCO, and acetyl chloride and gives various enantioenriched alcohols with selectivity factors up to 105.