文摘
In this paper, a heuristic method is presented for the simultaneous solution of the synthesis and design problemsof batch plants. A detailed nonlinear program (NLP) model is developed that considers a superstructure torepresent all the configuration options for the plants. Usually, similar works in this area assume as a hardconstraint the use of single-product campaigns. In this work, mixed campaigns are introduced to pose problemswhere this is a significant condition. Specific scheduling constraints are formulated, and a resolution strategyis presented to solve the problem. This formulation is valid for multiproduct batch plants and a special typeof multipurpose plants where products follow different production paths sharing some but not all the stages.The approach is implemented for a Torula yeast, brandy, and bakery yeast production plant. To assess themethod, different mixed campaigns are modeled. Economical and synthesis, design, and operational resultsare also reported.