Introduction of Lanthanide(III) Chelates to Oligopeptides on Solid Phase

详细信息    查看全文

• 作者：Jari Peuralahti ; Harri Hakala ; Veli-Matti Mukkala ; Kristiina Loman ; Pertti Hurskainen ; Outi Mulari ; and Jari Hovinen
• 刊名：Bioconjugate Chemistry
• 出版年：2002
• 出版时间：July 2002
• 年：2002
• 卷：13
• 期：4
• 页码：870 - 875
• 全文大小：81K
• 年卷期：v.13,no.4(July 2002)
• ISSN：1520-4812

文摘

The synthesis of oligopeptide building blocks for the introduction of nonluminescent and luminescentlanthanide(III) chelates to the oligopeptide structure on the solid phase is described. The oligopeptideconjugates synthesized were used in DELFIA-based receptor binding assay (motilin) as well as inLANCE time-resolved fluorescence quenching assay (caspase-3).