Development of a Catalytic Aromatic Decarboxylation Reaction

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• 作者：Joshua S. Dickstein ; Carol A. Mulrooney ; Erin M. O'Brien ; Barbara J. Morgan ; Marisa C. Kozlowski
• 刊名：Organic Letters
• 出版年：2007
• 出版时间：June 21, 2007
• 年：2007
• 卷：9
• 期：13
• 页码：2441 - 2444
• 全文大小：115K
• 年卷期：v.9,no.13(June 21, 2007)
• ISSN：1523-7052

文摘

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A palladium-catalyzed aromatic decarboxylation reaction has been developed. With electron-rich aromatic acids, the reaction proceeds efficientlyunder fairly mild conditions in good yields. The method was useful with complex functionalized substrates containing hindered carboxylicacids.