Accumulation, Metabolism, and Depuration of Organotin Compounds in the Marine Mussels Mytilus graynus and Mytilus edulis under Natural Conditions

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• 作者：Takashi Suzuki ; Isao Yamamoto ; Hisashi Yamada ; Nahoko Kaniwa ; Kazunari Kondo ; and Mitsunori Murayama
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：1998
• 出版时间：January 1998
• 年：1998
• 卷：46
• 期：1
• 页码：304 - 313
• 全文大小：261K
• 年卷期：v.46,no.1(January 1998)
• ISSN：1520-5118

文摘

The accumulation, transformation, and depuration oftri-n-butyltin (TBT) were studied over periodsof ~60-70 days using marine mussels, Mytilus graynus andMytilus edulis, under naturalconditions.M. graynus collected at a lightly polluted site weretransplanted to a highly polluted site and M.edulis collected at a highly polluted site were transplanted to alightly polluted site. TBT taken upin M. graynus showed a bioconcentration factor of 10 500 inthe accumulation phase. Di-n-butyl(3-oxobutyl)tin, which is a main metabolite of TBT in M.edulis, showed a longer half-life (8.13days) than that of the parent compound (4.82 days) in the depurationphase. On the other hand,another metabolite, di-n-butyl(3-hydroxybutyl)tin,showed a shorter half-life (3.98 days) than thatof the parent compound. The different half-lives among TBT and itsmetabolites are responsiblefor the different metabolic patterns in blue mussels at each samplingtime.Keywords: Organotin; TBTO; TBT; accumulation; depuration; elimination;metabolism; bluemussels; Mytilus graynus; Mytilus edulis;half-life; bioconcentration factor; BCF