Recent Development of Cardiac Troponin I Detection
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- 作者：Xu Han ; Shanghao Li ; Zhili Peng ; Abdelhameed M. Othman ; Roger Leblanc
- 刊名：ACS Sensor
- 出版年：2016
- 出版时间：February 26, 2016
- 年：2016
- 卷：1
- 期：2
- 页码：106-114
- 全文大小：537K
- ISSN：2379-3694
文摘
Cardiovascular disease (CVD) has threatened human lives for decades, and a technique for estimating and healing is still needed. There has been increasing interest in finding CVD diagnostic biomarkers to predict risk. Cardiac troponin I (cTnI) has proven to be a significant biomarker for acute myocardial infarction detection. An immunoassay based biosensor for cTnI can play an important role in diagnosis of CVD. Over the past decades, various methodologies regarding cTnI detection have been studied, including colorimetric, fluorescence, paramagnetic, electrochemical, and surface plasmon resonance. This review will focus more on recent strategies about surface immobilized cTnI detection.