Junction Probes − Sequence Specific Detection of Nucleic Acids via Template Enhanced Hybridization Processes

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• 作者：Shizuka Nakayama ; Lei Yan ; Herman O. Sintim
• 刊名：Journal of the American Chemical Society
• 出版年：2008
• 出版时间：September 24, 2008
• 年：2008
• 卷：130
• 期：38
• 页码：12560-12561
• 全文大小：137K
• 年卷期：v.130,no.38(September 24, 2008)
• ISSN：1520-5126

文摘

Junction probe nucleic acid detection technology allows the amplified sensing of analytes at isothermal conditions. The addition of a second dimension to detection probes permits the use of cheap commercially available DNA processing enzymes such as restriction endonucleases to detect single nucleotide polymorphisms, SNPs.