Absolute Configuration of 8-Amino-3,8-dideoxyoct-2-ulosonic Acid, the Chemical Hallmark of Lipopolysaccharides of the Genus Shewanella§
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- 作者：Serena Leone ; Antonio Molinaro ; Cristina De Castro ; Andreas Baier ; Evgeny L. Nazarenko ; Rosa Lanzetta ; Michelangelo Parrilli
- 刊名：Journal of Natural Products
- 出版年：2007
- 出版时间：October 2007
- 年：2007
- 卷：70
- 期：10
- 页码：1624 - 1627
- 全文大小：163K
- 年卷期：v.70,no.10(October 2007)
- ISSN：1520-6025
文摘
The novel monosaccharide 8-amino-3,8-dideoxyoct-2-ulosonic acid (Kdo8N) was isolated by methanolysis from the lipooligosaccharide of the marine Gram-negative bacterium Shewanella pacifica. After HPLC purification, the absolute configuration was determined by the Mosher ester method and proven to be 4R,5R,6R,7R. This established the D-manno- configuration of the monosaccharide.