Rearrangement of Pyridine to Its 2-Carbene Tautomer Mediated by Iridium

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• 作者：Eleuterio Á ; lvarez ; Salvador Conejero ; Patricia Lara ; Jorge A. L&oacute ; pez ; Margarita Paneque ; Ana Petronilho ; Manuel L. Poveda ; Diego del Rí ; o ; Oracio Serrano ; Ernesto Carmona
• 刊名：Journal of the American Chemical Society
• 出版年：2007
• 出版时间：November 21, 2007
• 年：2007
• 卷：129
• 期：46
• 页码：14130 - 14131
• 全文大小：73K
• 年卷期：v.129,no.46(November 21, 2007)
• ISSN：1520-5126

文摘

One of the Ir-CH₂ bonds within the chelate structure of compound 1 acts as a C-H activation shuttle and permits the 1,2-H shift needed for the isomerization of pyridine to its 2-carbene tautomer. The iridium-mediated tautomerization is kinetically competitive with traditionally facile N coordination of the heterocycle.