Efficient Synthesis of 3-Arylphthalides using Palladium-Catalyzed Arylation of Aldehydes with Organoboronic Acids

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• 作者：Masami Kuriyama ; Natsuki Ishiyama ; Rumiko Shimazawa ; Ryuichi Shirai ; Osamu Onomura
• 刊名：Journal of Organic Chemistry
• 出版年：2009
• 出版时间：December 4, 2009
• 年：2009
• 卷：74
• 期：23
• 页码：9210-9213
• 全文大小：742K
• 年卷期：v.74,no.23(December 4, 2009)
• ISSN：1520-6904

文摘

The synthesis of 3-arylphthalides via palladium-catalyzed arylation of aldehydes with organoboronic acids was achieved using the thioether-imidazolinium carbene ligand in good to excellent yields and was carried out using 1.0 mol % of the catalyst with high substrate tolerance.