Synthesis of Highly Functionalized 9,10-Phenanthrenequinones by Oxidative Coupling Using MoCl5

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• 作者：Simon Trosien ; Siegfried R. Waldvogel
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：June 15, 2012
• 年：2012
• 卷：14
• 期：12
• 页码：2976-2979
• 全文大小：231K
• 年卷期：v.14,no.12(June 15, 2012)
• ISSN：1523-7052

文摘

The strong oxidative power of molybdenum pentachloride gives rise to an efficient oxidative C鈥揅 bond formation of benzil derivatives to the corresponding 9,10-phenanthrenequinones. A highly complementary method to previous approaches was developed. The required derivatives are accessible in a modular fashion and in excellent yields. By this approach the orchid-derived natural product cypripediquinone A was synthesized for the first time.