Catalytic Chain-Breaking Pyridinol Antioxidants

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• 作者：Sangit Kumar ; Henrik Johansson ; Takahiro Kanda ; Lars Engman ; Thomas Mü ; ller ; Mats Jonsson ; Gian Franco Pedulli ; Silvia Petrucci ; Luca Valgimigli
• 刊名：Organic Letters
• 出版年：2008
• 出版时间：November 6, 2008
• 年：2008
• 卷：10
• 期：21
• 页码：4895-4898
• 全文大小：152K
• 年卷期：v.10,no.21(November 6, 2008)
• ISSN：1523-7052

文摘

When assayed for their capacity to inhibit azo-initiated peroxidation of linoleic acid in a water/chlorobenzene two-phase system, tellurium-containing 3-pyridinols were readily regenerable by N-acetylcysteine contained in the aqueous phase. The best inhibitors quenched peroxyl radicals more efficiently than α-tocopherol, and the duration of inhibition was limited only by the availability of the thiol reducing agent. The compounds were also found to catalyze reduction of hydrogen peroxide in the presence of thiol reducing agent.