Tetraquinanes via [4 + 4] Photocycloaddition/Transannular Ring Closure

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• 作者：Peiling Chen ; Patrick J. Carroll ; Scott McN. Sieburth
• 刊名：Organic Letters
• 出版年：2010
• 出版时间：October 15, 2010
• 年：2010
• 卷：12
• 期：20
• 页码：4510-4512
• 全文大小：189K
• 年卷期：v.12,no.20(October 15, 2010)
• ISSN：1523-7052

文摘

Intramolecular [4 + 4] photocycloaddition of a furan and a cyclopentane-annulated 2-pyridone yields a cyclooctadiene product with four new stereogenic centers. Transannular ring closure produces the 5−5−5−5 fused ring system of the crinipellins, including three contiguous quaternary carbons, with the correct absolute stereochemistry derived from (−)-carvone.