Photochemical Cleavage of Benzylic C–N Bond To Release Amines

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• 作者：Pengfei Wang ; Dattatray A. Devalankar ; Wenya Lu
• 刊名：Journal of Organic Chemistry
• 出版年：2016
• 出版时间：August 5, 2016
• 年：2016
• 卷：81
• 期：15
• 页码：6195-6200
• 全文大小：304K
• 年卷期：0
• ISSN：1520-6904

文摘

The 3-(diethylamino)benzyl (DEABn) group has been studied for releasing primary, secondary, and tertiary amines by direct photochemical breaking of the benzylic C–N bond. While photochemical release of primary and secondary amines provides high yields in methanol, release of tertiary amines in MeCN/water can improve yields and reduce the undesired dealkylation side reaction.