Antimicrobial Furostanol Saponins from the Seeds of Capsicum annuum L. Var. acuminatum

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• 作者：Maria Iorizzi ; Virginia Lanzotti ; Giancarlo Ranalli ; Simona De Marino ; and Franco Zollo
• 刊名：Journal of Agricultural and Food Chemistry
• 出版年：2002
• 出版时间：July 17, 2002
• 年：2002
• 卷：50
• 期：15
• 页码：4310 - 4316
• 全文大小：88K
• 年卷期：v.50,no.15(July 17, 2002)
• ISSN：1520-5118

文摘

Three new furostanol saponins named capsicoside E (1), capsicoside F (2), and capsicoside G (5)were obtained from the seeds of Capsicum annuum L. var. acuminatum along with knownoligoglycosides (3, 4, and 6-10). On the basis of chemical and spectroscopic analyses, the structuresof these new furostanol oligoglycosides were elucidated as 26-O--D-glucopyranosyl-22-O-methyl-5-furost-25(27)-en-2,3,22,26-tetraol-3-O--D-glucopyranosyl(13)--D-glucopyranosyl(12)-[-D-glucopyranosyl(13)]--D-glucopyranosyl(14)--D-galactopyranoside (1), 26-O--D-glucopyranosyl-(25R)-5-furost-20(22)-en-2,3,26-triol-3-O--D-glucopyranosyl (13)--D-glucopyranosyl(12)-[-D-glucopyranosyl(13)]--D-glucopyranosyl(14)--D-galactopyranoside (2), and 26-O--D-gluco-pyranosyl-(25R)-5-furosta-3,22,26-triol-3-O--D-glucopyranosyl(13)--D-glucopyranosyl(12)-[-D-glucopyranosyl(13)]--D-glucopyranosyl(14)--D-galactopyranoside (5). The isolated saponinsshowed higher antimicrobial activity against yeasts than against common fungi. Data indicated thatthe antiyeast activity was related to the combination of the oligosaccharide chain (S1, S2, or S3) withan O-methyl group at R₃ and the presence of a hydroxyl group at the C-2 position.Keywords: Capsicum annuum L.; Solanaceae; red pepper; seeds; furostanol saponins; antiyeastactivity