Copper-Catalyzed Trifluoromethylation of Polysubstituted Alkenes Assisted by Decarboxylation
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- 作者：Zhengbiao He ; Ping Tan ; Jinbo Hu
- 刊名：Organic Letters
- 出版年：2016
- 出版时间：January 4, 2016
- 年：2016
- 卷：18
- 期：1
- 页码：72-75
- 全文大小：341K
- ISSN：1523-7052
文摘
An efficient copper-catalyzed trifluoromethylation of polysubstituted alkenes assisted by decarboxylation of β,γ-unsaturated carboxylic acids has been achieved. The reaction provides a general method to construct allylic and vinylic CF3-substituted compounds under mild conditions.