Sulfinyl-Mediated Stereoselective Overman Rearrangements and Diels鈥揂lder Cycloadditions

详细信息    查看全文

• 作者：Roberto Fern谩ndez de la Pradilla ; Ignacio Colomer ; Alma Viso
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：June 15, 2012
• 年：2012
• 卷：14
• 期：12
• 页码：3068-3071
• 全文大小：257K
• 年卷期：v.14,no.12(June 15, 2012)
• ISSN：1523-7052

文摘

The Overman rearrangement of allylic sulfinyl trichloroacetimidates affords sulfinyl trichloroacetamides with high stereoselectivity and excellent yields. Bis-allylic substrates lead to amido 2-sulfinyl butadiene derivatives in excellent yields, with total chemo- and diastereoselectivity. The Diels鈥揂lder cycloaddition of related dienes is controlled by the sulfoxide moiety.