An Improved Procedure for Preparation of Carbapenem Antibiotic: Meropenem

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• 作者：Neera Tewari ; Hashim Nizar ; Bishwa Prakash Rai ; Shailendra K Singh ; Vinod George ; Mohan Prasad
• 刊名：Organic Process Research & Development
• 出版年：2007
• 出版时间：July 2007
• 年：2007
• 卷：11
• 期：4
• 页码：773 - 775
• 全文大小：40K
• 年卷期：v.11,no.4(July 2007)
• ISSN：1520-586X

文摘

An efficient synthesis of a 1-methyl carbapenem antibiotic,meropenem, is described. The present process does not involvecryogenic temperatures, chromatographic purification, or reverse osmosis and is amenable to large scale synthesis.