Communicating Chemical Congregation: A Molecular AND Logic Gate with Three Chemical Inputs as a "Lab-on-a-Molecule" Prototype

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• 作者：David C. Magri ; Gareth J. Brown ; Gareth D. McClean ; and A. Prasanna de Silva
• 刊名：Journal of the American Chemical Society
• 出版年：2006
• 出版时间：April 19, 2006
• 年：2006
• 卷：128
• 期：15
• 页码：4950 - 4951
• 全文大小：58K
• 年卷期：v.128,no.15(April 19, 2006)
• ISSN：1520-5126

文摘

We demonstrate the first three-input molecular AND logic gate based on three chemical inputs as a direct way of detecting congregations of chemical species. The AND gate operates in water and responds to Na⁺, H⁺, and Zn²⁺ inputs with an enhanced fluorescence signal when pre-set concentration thresholds are exceeded. Future "lab-on-a-molecule" devices could have application in medicine for rapid disease screening.