Three-Component Coupling Reaction Triggered by Insertion of Arynes into the S鈺怬 Bond of DMSO

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• 作者：Feng-Lei Liu ; Jia-Rong Chen ; You-Quan Zou ; Qiang Wei ; Wen-Jing Xiao
• 刊名：Organic Letters
• 出版年：2014
• 出版时间：July 18, 2014
• 年：2014
• 卷：16
• 期：14
• 页码：3768-3771
• 全文大小：287K
• ISSN：1523-7052

文摘

An unprecedented three-component coupling reaction of arynes, 伪-bromo carbonyl compounds, and DMSO triggered by insertion of arynes into the S鈺怬 bond of DMSO has been developed. The reaction can generate a wide range of multisubstituted aryl methyl thioethers in good yields, wherein DMSO serves as both methylthiolation reagent and oxygen source.