文摘
Eight new clerodane diterpenes, balanspenes A鈥揌 (1鈥?b>8), along with two known analogues (9 and 10), were isolated from the twigs of Casearia balansae. The structures of 1鈥?b>8 were elucidated on the basis of extensive 1D and 2D NMR spectroscopic data analysis, and the absolute configurations of compounds 1, 4, and 7 were confirmed by comparing their experimental CD spectra with those calculated by the time-dependent density functional theory method. Compounds 4鈥?b>7, 9, and 10 were found to possess the property of being able to stimulate NGF-mediated neurite outgrowth from PC12 cells.