Organocatalytic Conjugate Addition of Formaldehyde N,N-Dialkylhydrazones to , 详细信息    查看全文

• 作者：Raquel P. Herrera ; David Monge ; Eloí ; sa Martí ; n-Zamora ; Rosario Ferná ; ndez ; José ; M. Lassaletta
• 刊名：Organic Letters
• 出版年：2007
• 出版时间：August 16, 2007
• 年：2007
• 卷：9
• 期：17
• 页码：3303 - 3306
• 全文大小：75K
• 年卷期：v.9,no.17(August 16, 2007)
• ISSN：1523-7052

文摘

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(1S,2R)-1-Aminoindan-2-ol-derived thioureas behave as efficient H-bonding organocatalysts for the nucleophilic conjugate addition of formaldehydehydrazones to ,-unsaturated -keto esters as enoate surrogates, affording the corresponding adducts in good yields and enantioselectivities.