We describe accommodations that we have made to our applied computational鈥搕heoretical chemistry laboratory to provide access for blind and visually impaired students interested in independent investigation of structure鈥揻unction relationships. Our approach utilizes tactile drawings, molecular model kits, existing software, Bash and Perl scripts written in-house, and three-dimensional printing in a process that allows a blind or visually impaired student to satisfy her or his curiosity about structure鈥揻unction relationships with minimal assistance from sighted co-workers.